What to do when KDE is unresponsive?

[D. R. Evans]

Twice in the past month I have had Konq freeze my desktop.

(When I say "freeze", it isn't really a freeze: everything keeps
working except that all mouse clicks are ignored.)

Both times that this has happened, I have ended up rebooting my
machine (by hitting ctrl-alt-F1 to open a console). Is there any last
drastic action I could/should take the next time this happens?
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